Delia Sanchez- hotel hospitality manager, best-selling writer, ghost conduit, and new mom - is busy preparing the charmingly-haunted Loring Boutique Hotel to host the remaining survivors of a drug trial conducted twenty years ago. They've reunited for a fundraising venture to benefit the financially-strapped Stevensen Memorial Hospital that helped cure them of childhood cancer. Delia's also putting the finishing touches on her fast-approaching Valentine's Day wedding to fiance Gabe. Unfortunately, an unexpected and unwelcome guest throws Delia's preparations into a tailspin. Tallulah Mimowsky, Gabe's ex-wife, has invited herself to the wedding.

Events go from bad to worse when a hooded intruder threatens Delia's cat Esmeralda, poisons a guest who accidentally eats that cat's gourmet meal, and finally gases someone else almost to death. These events challenge Delia with life-altering questions: Who is trying to murder her cat? Did she really see the Angel of Death in the hotel's lobby - and if so, for whom did the Angel come? Most importantly, can Delia clean up the mess before saying her wedding vows?