The Red Hands symbolize the ongoing crisis of missing and murdered Indigenous women in the United States, particularly among Native American communities. The red handprint is often seen painted across the mouth of those advocating for this movement, representing the silenced voices of these women who have been victims of violence, kidnapping, or murder, often without proper investigation or justice. This crisis is rooted in a long history of systemic marginalization, lack of proper law enforcement response, and jurisdictional challenges. In this novel, add the unsolved serial killer known as the Zodiac Killer, and this murderer could be involved in the ongoing crisis of the missing and murdered Indigenous women in the Native communities. This Zodiac Killer leaves behind clues in the form of letters and ciphers regarding these missing and murdered Native women and in the case of one murdered Native woman who is killed in Sheridan County, Wyoming, where Mary MacIntosh is left prosecuting the case. Who is the infamous Zodiac Killer and is it really him from the late 1960s and early 1970s, or is it a copycat killer? Mac must solve this puzzle before another Indigenous woman is killed.