'Big Mike' O'Donahue has accepted a role as a US Marshal and is trailing a group of felons to the Mountains of New Mexico.

Meanwhile, his family is being set up for an ambush in New York by their common enemy, Melvin J. Harvington.

The kidnapping of Big Mike's wife turns into a pursuit where the Old Bear gets on the trail to find his wife. Driven by fear and fury, the pursuit goes all the way to Old Mexico.

The rest of Mike's family must fight their way back West and find a way to reunite with him.