BRAIN GRAFT centres around Isobella, who works at a publishing firm and is diagnosed with a brain tumour. She finds a surgeon to remove her tumour and decides to have a brain implant - that is, a segment of brain to fill the space in her brain created by the tumour removal. The segment is donated by another woman, Tracey.After the transplant, Isobella begins to take on characteristics of Tracey’s personality. Isobella’s boyfriend, Tarquin, is horrified by this. Isobella begins a slow but steady slide down the socio-economic ladder, losing her job and sitting around the flat all day. Tracey’s trajectory is the opposite. She takes a job cleaning at a hospital, where she meets David, a nurse, who encourages her to study for a nursing diploma.Tracey lands a job as a nurse at a psychiatric hospital, which is where, in the final scene, she crosses paths with Isobella who has been dumped there by an exasperated Tarquin. David has, by this time, dumped Tracey, claiming that he loved her only because he was seeing the world through rose-tinted spectacles due to the anti-depressants he was on. The two women decide to become lesbian lovers.