Human Ageing: A Unique Experience - Implications For The Disease Concept

Michael Alan Singer (Queen's Univ, Canada)

Human Ageing: A Unique Experience - Implications For The Disease Concept
Format
Hardback
Publisher
World Scientific Publishing Co Pte Ltd
Country
Singapore
Published
13 March 2015
Pages
336
ISBN
9789814619127

Human Ageing: A Unique Experience - Implications For The Disease Concept

Michael Alan Singer (Queen's Univ, Canada)

Human Ageing: A Unique Experience explores the biology of human ageing focusing on the individual. The book begins with the premature ageing disorder Hutchinson-Gilford Progeria syndrome and spins a web of interconnected biological domains involving lamins, telomeres, alternative splicing, genetics, epigenetics, and molecular clocks. The profound influence of culture is explored since cultural inheritance and genetic inheritance are the two intertwined processes driving human evolution. An empirical framework is developed to describe human ageing at the individual level and the implications of this framework on the whole concept of diseases are discussed.

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