In the Western Pacific Region, more than 100 million people are affected by mental disorders - many of which can be prevented or managed with cost-effective interventions. These interventions would improve the quality of life of those affected, as well as reduce the total disease burden. The resulting windfall would promote economic growth at community, national and regional levels. The regional agenda features a phased approach to achieve the four objectives: (1) strengthen effective leadership and governance for mental health; (2) provide comprehensive, integrated and responsive mental health and social care services in community-based settings; (3) implement strategies for the promotion of mental health and the prevention of mental illness; and (4) strengthen information systems, evidence and research for mental health.