Peptides: Chemistry, Structure and Biology

This unique reference book contains 372 articles selected from 762 plenary lectures, workshops and poster presentations made during the Thirteenth American Peptide Symposium held in Edmonton, Alberta, Canada.

The book opens with Nobel Laureate Dr. Bruce Merrifield’s “Remarks on Peptide Chemistry’ which focus on past scientists and their contributions of peptide chemistry in all aspects of biology, and Dr. Victor Hruby’s Pierce Award Lecture on designing peptides, pseudopeptides and peptidomimetics to understand the relationship between structure and biology activity. The contributions are grouped into 14 sections:

Synthetic and Analytical Methods

Peptide Mimetics

Glycopeptides/Lipopeptides

Peptide Hormones/Neuropeptides

Peptide Inhibitors/Peptide-Receptor Interactions

Peptide Vaccines and Immunology

Conformational Analysis

Peptide Pharmaceuticals/Diagnostics and Peptide Delivery

Computational Biochemistry

Peptide Macromolecular Interactions

Peptide Libraries

De novo Design of Peptides and Proteins;

and three Workshops:

Approaches and Advances in Peptide Synthesis, Purification and Analysis

An Introduction to NMR Spectroscopy of Peptides

An Introduction to Energy Minimization, Molecular Dynamics, Molecular Modelling and Conformational Analysis of Peptides.

This 1200 page compendium of current research from both academic and industrial laboratories demonstrates the exponential growth of the use of peptides in the diverse fields of medical science.