This Volume of the Series is devoted to aging at the organismic level. Different levels of organisation, ranging from single cell organisms (yeast) to humans are included. In addition to the currently most important model systems like yeast, filamentous fungi, Caenorabditis elegans, flies and mice, other systems like sponges and plants are discussed. Most importantly, research using different aging models can be expected to unravel the most important basic mechanisms of aging that are conserved in all species. In addition, a critical discussion of what can be expected from this kind of strategy for the understanding of aging in humans is included. This book serves as excellent reading for graduate students, scientists in Medical Research, Medical doctors, researchers in pharmacological fields, researchers, biologists, and experts of this area.