The integration of manufacturing constraints and their optimization in the design process is becoming more and more widespread in the development of mechanical products or systems. There is a clear industrial need for these kinds of methodologies. Important - but still unsolved - problems are related to the definition of design processes, the choice of optimal manufacturing processes and their integration through coherent methodologies in adapted environments. The main topics addressed in this book are: *design theory: process and modeling, *control, measurement and tolerancing, *manufacturing: modeling and planning, *optimal design of machines, structures and components. The book provides original information from authors who are involved in very recent research in the field. Beyond the theoretical background, the main focus is the relation of the research to industrial applications for most of the articles. The book is dedicated to engineers, researchers and PhD students who are involved in the domain of the optimisation of the design and the manufacturing processes.