Regenerative Endodontics

Pulpal and peri radicular pathosis, which can be caused by caries, trauma, or dental abnormalities, is a common disease in clinic for dental treatment. Root canal treatment (RCT) is a conventional option to manage the endodontic diseases in fully developed permanent teeth demonstrating outstanding clinical outcomes, while apexification procedure is the traditional treatment modality for the immature permanent teeth with pulp necrosis. However, these treatment procedures remove the pulp and some dentin tissues, which weaken the dentinal strength, immunological responses and proprioceptive functions, leading to a higher risk of reinfection and tooth fracture. Regenerative endodontics uses the concept of tissue engineering to restore the root canals to a healthy state, allowing for continued development of the root and surrounding tissue. Endodontists' knowledge in the fields of pulp biology, dental trauma, and tissue engineering can be applied to deliver biologically based regenerative endodontic treatment of necrotic immature permanent teeth.These developments in the regeneration of a functional pulp-dentin complex have a promising impact on efforts to retain the natural dentition.