Human ageing is a process characterised by both biological and physiological changes with repercussions in terms of altered body composition, with an increase in adipose tissue giving rise to chronic inflammation, indicated by an increase in inflammatory markers. This series of factors leads to cardiovascular risks, increasing morbidity and mortality in this population. Resistance training (RT) carried out on a regular basis offers adaptation and beneficial changes to the body, protecting it against various types of disease and causes of mortality, especially cardiovascular disease. On the other hand, its interruption leads to a decline in these adaptations, resulting in the reappearance of diseases and morbidities. This book shows the positive influence of resistance training, as well as the deleterious consequences of detraining on risk parameters for CVD represented by serum concentrations of C-Reactive Protein, lipid profile, as well as body composition in elderly women.