Carob (Ceratonia siliqua L.), belongs to the family of Leguminosae, with numerous applications as food additive materials. Its pods have been utilized for both human and animal food purposes in traditional medicinal sciences for many years. Honey comb has been used for thousands of years in TCM to treat many diseases, such as rheumatoid arthritis, digestive and urinary disorders, dental diseases, and cancer, however, studies have focused on the antibacterial, anti-inflammatory and anti-caner activities of it.