Formulation and evaluation of hydrogel

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The data obtained from the study of, Formulation and Evaluation of hydrogel containing antimicrobial drug (Azithromycin) and silver nanoparticles reveals that Silver nanoparticles were reported to have good antimicrobial activity in lower concentration and can combine with other antimicrobial agent to get synergistic effect.The Silver nanoparticles were prepared by green synthesis approach with the help of reduction ofsilver nitrate by Azadirachta indica leaves extract. Azithromycin was chosen as antimicrobial drug, however it shows adverse effect when administered in high dose, hence to reduce dose of azithromycin it was decided to make formulation containing silver nanoparticles and azithromycin.The drug loading and drug delivery techniques were searched for topical as well as bone grafting purpose.