The Tohoku University Graduate School of Dentistry has proposed Interface Oral Health Science as the main theme of next-generation dental research since 2002. That theme is based on the new concept that healthy oral function is provided by biological and biomechanical harmony among three systems: oral tissues, parasites, and biomaterials, and that oral diseases are interpreted as interface diseases caused by disruption of the intact interfaces among those systems. The Second International Symposium was organized to promote advances in dental research and to activate interdisciplinary research with related fields by putting interface oral health science into practice. Researchers at the global forefront of the field participated in the symposium, the contents of which are summarized in this book. Also included are the text of a lecture by the president of Tohoku University, an educational lecture by the vice-dean of King’s College London Dental Institute, the contents of three symposia and more than 70 poster presentations.