Lipoprotein Metabolism and Atherogenesis

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The major cause of death in industrialized societies is atherosclerosis, which leads to coronary heart disease and cerebrovascular disorders. Researchers have discovered that the earliest event in atherogenesis is the adhesion of circulating leukocytes to the vascular endothelial cells. The complicated process that follows is being unravelled by intensive studies in molecular biology. The identification of the genes involved has been verified by the creation of novel animal models, which in turn has led to new therapeutic strategies for atherosclerosis. These and other important findings are contained in the proceedings of the International Symposium on Lipoprotein Metabolism and Atherogenesis. This volume presents the results of research in the areas of the molecular basis of lipoprotein metabolism, the link between lipoprotein metabolism disorder and atherogenesis, and the molecular approaches to risk factors and prevention.