Engineering and Characterisation of Novel Nanomedicine Formulations

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Over the last few decades, nanomedicine has become a hot topic in formulation science regarding selectively delivering drugs to target tissues. Nanomedicines can modify drug release and encapsulate poorly soluble drugs, allowing for a selective targeting and minimizing adverse effects. This is of key importance in antitumoral and anti-infectious therapies, in which undesired drug release can lead to severe damage to healthy tissues. Moreover, they protect drugs from degradation, allowing for the the delivery of RNA. This reprint encompasses works describing the design, development and characterization of lipid nanomedicines, dendrimers and virus nanoparticles among others, as well as the evaluation of their toxicity and their anticancer and antifungal efficacy. Moreover, it analyzes the quality assessment of nanomedicines under clinical investigation.