Detection of Some Immunologic and Genetic Factors of Psoriasis Patient

This title is printed to order. This book may have been self-published. If so, we cannot guarantee the quality of the content. In the main most books will have gone through the editing process however some may not. We therefore suggest that you be aware of this before ordering this book. If in doubt check either the author or publisher’s details as we are unable to accept any returns unless they are faulty. Please contact us if you have any questions.

This study aimed to investigating the host susceptibility to the psoriasis and the association of (Rs1184860, Rs1167846 and Rs1167849) single nucleotide polymorphisms (SNPs) in the Interleukin -20 Receptor A (IL- 20RA) gene, located on chromosome 6q22.33-23.1, and detecting late cornified envelope 3B and late cornified envelope 3C (LCE3B and LCE3C) genes mutations. These genes encode members of late cornified envelope gene cluster, and are in the region that contains the Psoriasis Susceptibility gene-4 (PSORS4) locus on chromosome 1q21, and the role of interleukins (IL-17A, IL-23) and Human papillomavirus in the pathogenesis of this disease.