Conjugation-Deconjugation Reactions in Drug Metabolism and Toxicity

Conjugation-Deconjugation Reactions in Drug Metabolism and Toxicity
Format
Paperback
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Country
Germany
Published
22 November 2011
Pages
530
ISBN
9783642784316

Conjugation-Deconjugation Reactions in Drug Metabolism and Toxicity

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In-depth coverage of advances in molecular biology, indicating the importance of drug and xenobiotic conjugates as transport forms of biologically active compounds. Part One describes molecular events associated with the expression and regulation of transferases and hydrolases involved in Phase II drug conjugation and deconjugation. Part Two deals with the regulation of Phase II conjugation, while Part Three critically reviews the importance of drug conjugates in pharmacology and toxicology. An up-to-date source of information of broad interest to pharmacologists and toxicologists.

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