This handbook is intended for the advanced specialist and for the practitioner interested in the application of lasers in medicine. It provides state-of-the art summaries of all available medical laser systems and the indications for their clinical use. The first part introduces basic laser physics, including laser-tissue interactions as well as technical equipment and particular techniques developed for medical use in connection with laser. The second part of the text covers all areas of laser application in medicine presented by senior specialists from different countries, each having extensive practical experience.