In several applications it is well recognized that all materials, on some scale, cannot be regarded as perfect continua. They rather contain a variety of numerous defects, such as micro-cracks, inclusions, vacancies, voids, dislocations, etc. To characterize such defects, the notion of force acting on a defect in the material needs to be introduced, which leads to a whole engineering science of Configurational Mechanics of Materials . The lecture notes cover the numerous elements of configurational mechanics, including mathematical foundations, linear and nonlinear elasticity and continuum mechanics, coupled fields, fracture mechanics, as well as strength-of-materials.