This volume presents the proceedings of the conference 'Ministerium Sermonis. An International Colloquium on St. Augustine's Sermons' (8-10 December 2021). The nineteen articles collected here focus on the transmission, critical edition, interpretation, and reception of Latin Patristic sermons, and particularly the sermons of the African Church Father Augustine of Hippo. By combining philological, exegetical, theological, rhetorical, and historical approaches, this volume aims to demonstrate the value of these sermons as a key source for understanding the Early Christian Church. The volume forms a sequel to the proceedings of the previous three Ministerium Sermonis conferences (Leuven-Turnhout 2008, Rome 2011, Malta 2015), which have also been published in the series Instrumenta Patristica et Mediaeualia (subseries Ministerium Sermonis I, II, III).