This volume publishes a new Coptic handbook of ritual power, comprising a complete 20 page parchment codex from the second half of the first millennium AD. It consists of an invocation including both Christian and Gnostic elements, ritual instructions, and a list of twenty-seven spells to cure demonic possession, various ailments, the effects of magic, or to bring success in love and business. The codex is not only a substantial new addition to the corpus of magical texts from Egypt, but, in its opening invocation, also provides new evidence for Sethian Gnostic thought in Coptic texts. A Coptic Handbook of Ritual Power is the first volume in the series The Macquarie Papyri, which will publish the papyri in the collection of the Museum of Ancient Cultures, Macquarie University (Sydney, Australia).