Williams Carter Wickham, a Confederate general, opposed secession, supported Reconstruction, and later led the Chesapeake and Ohio Railroad.

Williams Carter Wickham fought bravely for the south as a Confederate cavalry officer, finishing the war as a brigadier general. He also steadfastly opposed secession, believing that it was illegal. From a prominent Virginia family, he was a natural leader in the field and, late in the war, Confederate Congress. He rose from the rank of captain and after the war broke with his fellow generals by joining the Republican Party, urging compliance with Reconstruction. He became an organizer of railroad improvements and expansion, becoming leader of the Chesapeake and Ohio Railroad and served in the Virginia State Senate.