Anne and Joe have at long last found the sweet spot in their relationship - they have overcome conflict and difficulties and the challenges of growing towards old age together, and now appreciate each other’s company, a great sex life, and are looking forward to what retirement brings.

But inexplicably, Joe - a gifted architect - finds himself losing things, making miscalculations and blanking out parts of his day.

As Joe’s condition worsens, he and Anne face the agonising question: what is the point of no return?