Over the last fifteen years a large collection of protozoan parasite genomes have been sequenced, annotated and made available on public databases. This wealth of information has stimulated and fuelled new research into vaccine and drug discovery, new approaches for high-throughput experimentation and the genetic engeneering of key protozoan parasites. In this timely book expert international authors review the current hot-topics in this area to provide an up-to-date overview. The book is divided into two parts. The first part is dedicated to Trypanosoma cruzi, an organism not only responsible for a serious tropical disease but also a good model system for fundamental and applied biology research. Part two of the book is dedicated to four other important protozoa: Leishmania, Naegleria, Entamoeba and Acanthamoeba. Chapters are written from a molecular biology and genomics perspective and focus on a common goal: the development of new strategies for the control and prevention of infection. This volume is essential reading for anyone working on protozoan parasites in academia, government, and biotechnology companies.