This report presents the findings from one of the first evaluations of a British programme to integrate drug and alcohol treatment with mental health services, and education, training and employment support - the ‘From Dependency to Work (D2W)’ programme. It provides an invaluable insight into the challenges and difficulties of integrating services in this way and highlights important lessons for central and regional government on funding and working with the voluntary sector to deliver services. With the recent launch of the Drug Interventions Programme (DIP), designed to get statutory and voluntary sector agencies working together to tackle the social factors associated with drug misuse and crime, stakeholders across the country will need to develop effective multi-disciplinary working in this field. This report provides all those involved, from a strategic level to frontline practitioners, with a clearer understanding of the issues.