It is 1888 and Queen Victoria has remarried, taking as her new consort the Wallachian Prince infamously known as Count Dracula. His polluted bloodline spreads through London as its citizens increasingly choose to become vampires.

In the grim backstreets of Whitechapel, a killer known as ‘Silver Knife’ is cutting down vampire girls. The eternally young vampire Geneviere Dieudonne and Charles Beauregard of the Diogenes Club are drawn together as they both hunt the sadistic killer, bringing them ever closer to England’s most bloodthirsty ruler yet.