Nature puts a survival switch in our bodies to protect us from starvation. Stuck in the on position, it’s the hidden source of weight gain, heart disease, and many other common health struggles. But you can turn it off.

Dr. Richard Johnson has been on the cutting edge of research into the cause of obesity for more than a decade. His team’s discovery of the fructose-powered survival switch-a metabolic pathway that animals in nature turn on and off as needed, but that our modern diet has permanently fixed in the on position, where it becomes a fat switch-revolutionized the way we think about why we gain weight.

In Nature Wants Us to Be Fat, he details the mounting evidence on how this switch is responsible both for excess fat storage and for many of the major diseases endemic to the Western world, including heart disease, cancer, and dementia. Dr. Johnson also reveals the surprising link between the survival switch and health conditions such as gout, kidney disease, liver disease, stroke-and even behavioral issues like addiction and ADHD. And, most important, he shares a science-based plan to help readers fight back against nature.

Guided by ongoing clinical research-plus fascinating observations from the animal kingdom, evolution, and history-Dr. Johnson takes you along on an eye-opening investigation into-

. What you can do to turn off your survival switch

. What we have in common with hibernating bears, sperm whales, and the world’s fattest bird

. Why it’s fructose (not glucose) that drives insulin resistance and metabolic disease

. The foods we eat that trigger the body to make its own fructose

. The surprising role salt and dehydration play in fat accumulation

Dr. Johnson not only provides new recommendations for how we can prevent or treat obesity, but also how we can use this information to reduce our risk of developing disease. Nature wants us to be fat, and when we understand why, we gain the tools we need to lose weight and optimize our health.