Ventricular Arrhythmia: From Principles to Patients

Ventricular arrhythmias are the main cause of sudden arrhythmic death, a devastating situation that is tied to heart failure and its incidence is increasing despite current available therapies. This book reviews and explores the pathophysiology of ventricular arrhythmia and currently available therapeutic modalities including ion channel blockades, catheter ablation and defibrillators, with the hope that the wealth of accumulated science and knowledge have grown to the point that with the help of current advanced technology which allows targeting cellular, molecular and genetic components, a paradigm shift in treatment of these deadliest arrhythmias becomes possible. The book also provides chapters on currently available pharmacological options, defibrillation and catheter ablation as well as chapters on new treatments and technologies such as cell and gene therapies and what may be the future of arrhythmia therapy.