Phosphodiesterase Methods and Protocols

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This volume provides a palette of a variety of conceptual and technical approaches, as well as tools in the PDE field allowing investigators to solve questions concerning the role of PDE isozyme and PDE isozyme tissue variants by addressing physiological functions or their implication in various pathologies. Phosphodiesterase Methods and Protocols will be invaluable to scientists, biochemists, molecular biologists, cell biologists and pharmacologists who wish to initiate or to deepen studies in the PDE field and to assist medicinal chemists and pharmaceutical reseachers in devising new approaches to drug design.