A recent upsurge of research examining inositol phospholipids (IP)-membrane-bound species fundamental to cell signaling-continues underscore the role of this pathway in both normal and disease-associated cellular physiology. This volume includes a selection of cutting-edge, multidisciplinary reports borne out of the conference Inositol Phospholipid Signaling in Physiology and Disease held June 26-27, 2012 at the New York Academy of Sciences in New York City. Papers include important developments investigating IP signaling in immunology, cancer, inflammation, and metabolic disorders.

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