Central and Eastern Europe together make up one of the areas of the world that has undergone profound transformations during the one hundred years delimited by the two Edinburgh gatherings that inspired the Regnum Edinburgh Centenary Series. It is the place in which Marxist ideology gave birth to the Communist hegemony that has impacted the European arena for over fifty years. But this is also the place where Christian churches experienced God’s grace and provision, and even unexpected flourishing in some quarters. The present volume brings together significant contributions from over thirty theologians, missiologists, and practitioners from this part of the world. The articles explore the complex missiological thinking and praxis of Central and Eastern Europe, highlight concrete missiological endeavors, and point to the challenges and opportunities for mission in this part of the world. It also includes relevant missiological documents that have emerged in the area within the past twenty-five years.