This study of the work of noted liberal theologian Gordon Kaufman tracks his career from his first published book, Relativism, Knowledge, and Faith (1960) through his 2006 book, Jesus and Creativity, in light of recent conversations about divine action and modern scientific knowledge. James interprets Kaufman’s mature position as a sophisticated reconstruction of divine activity that makes use of recent scientific theory and its naturalistic assumptions in order to revitalize a theocentric frame of reference rooted in classical theological tradition. Though there are costs to be paid in the construction of a theology of radical naturalism, particularly with respect to the relation between divine action and the human good, Kaufman’s program offers a distinctive way forward. After developing a critical analysis of the limitations and possibilities of Kaufman’s mature position, James suggests that a christological reconsideration of the meaning of human flourishing offers the prospect of an even more radically naturalistic and theocentric theology.