Approaching us in sovereign freedom, God comes alive to us, we come alive to God, and all creation comes alive as a sign pointing to God. In the gospel of Jesus Christ, God gives and discloses himself in this immediate way as our ultimate context and host, within the provisional medium of creation. This life-giving gospel is met by blindness, however, among those who live today in a collapsing Western culture. This is because their imaginative world is shaped by habitual assumptions and practices that lie–largely unacknowledged–deep within that culture, and that preclude openness to the gospel. Moreover, Western Christians themselves widely share these assumptions, betraying the gospel into cultural captivity. God calls for the conversion of Western culture to the living gospel. Crucially this must include, as Lesslie Newbigin recognized, a repentance from modern Western assumptions about knowledge. Part One explores seeking, knowing, and serving God, as providing a true paradigm for understanding all human enquiry, knowledge, and action. Part Two examines ten resulting hot spots where conversion from prevailing cultural assumptions is vital for authentic mission to Western culture.