Quantitative Methods for Precision Medicine: Pharmacogenomics in Action

Features:

Functional and systems mapping models to characterize the genetic architecture of multiple medication processes
Statistical methods for analyzing informative missing data in pharmacogenetic association studies
Functional graph theory of inferring genetic interaction networks from association data
Leveraging the concept of epistasis to capture its bidirectional, signed and weighted properties
Modeling gene-induced cell-cell crosstalk and its impact on drug response
A graph model of drug-drug interactions in combination therapies
Critical methodological issues to improve pharmacogenomic research as the cornerstone of precision medicine