Eastern spirituality has exerted considerable influence on the fields of counseling and psychology through the use of mindfulness-based practices. This book serves as a practical introduction to integrating mindfulness-based practices in therapy, with a focus on assessing whether it is appropriate to use or adapt mindfulness activities to the specific cultural identity or identities of clients. Interventions can be adapted to account for clients’ religious/spiritual identity, gender norms, racial/ethnic background, community values and pressures, personality traits, unfamiliarity with mindfulness-based practices, cognitive flexibility, and individual life experiences. The authors present an approach to integrating mindfulness in therapy that emphasizes cultural humility, which combines an accurate view of oneself (including limits in one’s awareness, knowledge, and skills for working with individuals from diverse groups) with the ability to cultivate an other-oriented stance, thus enhancing one’s ability to work with clients from a variety of cultural backgrounds. By incorporating this client-centered approach, therapists will be better able to align the therapy process with clients’ values, narratives about change, and therapy goals.