The Chalcolithic period (ca. 4500-3600 BCE) in the southern Levant represents the rise of regional polities, the metallurgical revolution, and a set of other significant socio-economic changes that distinguish it from the preceding Pottery Neolithic period. Central to these issues are the Phase II (1987-1989, 1993) excavations at Shiqmim, a large Chalcolithic settlement center in Israel's northern Negev desert. The first phase of excavations at Shiqmim took place between 1979 and 1984 and were described in Shiqmim I, Parts i and ii (BAR Publishing, 1987). Shiqmim II reports on the second phase of excavations at this complex site and contributes to a greater understanding of its Chalcolithic stratigraphy, architecture, and chronology. It includes the project research design and history framed in an anthropological archaeology perspective, primary excavation data, and a Bayesian analysis of radiocarbon dates from Shiqmim presented in comparison with dates from contemporary regional sites.