The Sodium-Hydrogen Exchanger: From Molecule to its Role in Disease

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This volume contains state-of-the art- reviews dealing with diverse aspects of the sodium-hydrogen exchange family of membrane transporters - from basic science to clinical relevance. It includes a wide spectrum of topics dealing with sodium-hydrogen exchange ranging from molecular to clinical and covers established and emerging concepts related to sodium-hydrogen exchange, including newly identified novel isoforms. There are also updates on completed and continuing clinical trials with sodium-hydrogen exchange inhibitors. The book should be of interest to pharmacologists, physiologists, biochemists, cell and molecular biologists and clinical scientists interested in new therapeutic concepts related to sodium-hydrogen exchange inhibition.