This publication is the proceedings of Relaxin 2000: The Third International Conference on the Hormone Relaxin and Related Peptides, held on October 22-27, 2000, at the Cable Beach Resort, Broome, Australia. Delegates from academia and industry who attended this meeting, participated in a scientific programme that covered all aspects of relaxin research. Seminal topics presented at the conference and in this book include: clinical roles for Relaxin; elucidation of novel sites of action of the hormone; Relaxin-induced signal transduction; identification of non-pregnant roles of the hormone; and of novel Relaxin-related peptides (particularly insl 3 and 5) and their possible synergistic actions with Relaxin.