One Girl Began entwines the stories of three women, separated by history but connected by the same building. For Ellen in 1909, it is a box factory where she finds work and a transformative circle of friendship when her family fall on hard times. For Frances in 1984, it is a derelict ruin, where she joins a group of squatters and is drawn into a coercive relationship. And for Amanda in 2020, it is a gentrified conversion, where she finds herself trapped in a tiny flat and grappling with new motherhood as the pandemic looms into view.

Over the span of 111 years these three women will come to haunt one another backwards and forwards in time, each immersed in the ripples of the lives that came before, and each struggling with the same questions of who to be and how to live.