Strategies to integrate NMR spectroscopy in-person and virtuallyNuclear magnetic resonance spectroscopy has grown to be an important part of the undergraduate curriculum; however, lack of access to chemical instrumentation and experiential learning has introduced a difficult challenge for educators. This work expands on topics covered in the first three volumes (1128, 1221, and 1225), including a new focus on approaches to incorporate NMR spectrometers into the curriculum for in-person and distance learning. Chapters explore the characterization of organic molecules and synthetic products using NMR, quantitative and computational methods employing NMR, and novel applications of multinuclear and multidimensional NMR.