Published in 2008, the first volume of Public Health focused on issues from the dawn of western civilization through the Progressive era. Volume 2 defines the public health challenges of the twentieth century–this important reference covers not only how the discipline addressed the problems of disease, but how it responded to economic, environmental, occupational, and social factors that impacted public health on a global scale. Major illnesses such as cancer, HIV, and tuberculosis are addressed, along with lifestyle concerns, such as tobacco and nutrition. Chapters also explore maternal-child and women’s health, dental public health, health economics and ethics, and the role of philanthropy. Each chapter begins with an in-depth introduction, followed by three original articles that illustrate the problem. The volume is enhanced with a detailed chronology of public health events, as well as appendices that contain many of the original documents that ushered public health into the new millennium.