Eastern Kentucky University (EKU) in Richmond, Kentucky, celebrated its centennial in 2006. EKU has had a colorful history, from the political quandaries surrounding the inception of its predecessor institutions to its financial difficulties during the Depression to its maturing as a leading regional university. Reflecting on the social, economic, and cultural changes in the region over the last century, William E. Ellis follows each university president’s administration in the context of the times. Interviews of alumni, faculty, staff, and political figures add to the story. A History of Eastern Kentucky University is an essential resource for those interested in a vital educational institution and in the progression of public higher education in Kentucky and the region.