TxNxM1: The Anatomy and Clinics of Metastatic Cancer

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Distant metastases are the most dreaded situation in the evolution of cance. Stimulated by the occurrence in his practice of some puzzling and unexpected metastases literature, the author reviewed more than 12,000 references. He looked for anatomical relationships highlighting the relation between the location of the primary tumors and the particular patterns of metastasis observed. The pathways and flows are apparently a more decisive factor in the implantation of the metastases than the seed and soil properties of the cancer cells and the metastatic site. Aided by his colleague Dr. T. Geukens, M.D., the author includes anatomical drawings, illustrating the sometimes unexpected pathways the cancer cells follow in order to reach the organs where they will become lodged and give rise to metastatic tumors.