This book introduces value distribution theory over non-Archimedean fields, starting with a survey of two Nevanlinna-type main theorems and defect relations for meromorphic functions and holomorphic curves. Secondly, it gives applications of the above theory to, for example, abc-conjecture, Waring’s problem, uniqueness theorems for meromorphic functions, and Malmquist-type theorems for differential equations over non-Archimedean fields. Next, iteration theory of rational and entire functions over non-Archimedean fields and Schmidt’s subspace theorems are studied. Finally, the book suggests some new problems for further research.