This collection presents insights of the key speakers of the interdisciplinary Einstein meets Magritte conference (1995, Brussels Free University). The contributions elaborate on fundamental questions of science, with regard to the 1990s world, and push beyond the borders of traditional approaches. All of the articles in this volume address this fundamental theme, but the volume expanded to become more than a mere expression of the conference’s dynamics. The articles not only deal with several scientific disciplines, they also confront these fields with the full spectrum of 1990s life, and become new science. The contributions are accessible to a large audience of scientists, students, educators, and everyone who wants to keep up with science at the end of the millennium.