This is the second volume of a two-volume monograph which obtains fundamental notions and results of the standard differential geometry of smooth manifolds, without using differential calculus. Here, the sheaf-theoretic character is emphasized. This has theoretical advantages such as greater perspective, clarity and unification, but also practical benefits ranging from elementary particle physics, via gauge theories and theoretical cosmology ( differential spaces ), to non-linear PDEs (generalized functions). Thus, more general applications, which are no longer smooth in the classical sense, can be coped with. The treatise might also be construed as a new systematic endeavour to confront the ever-increasing notion that the world around us is far from being smooth enough . This work is intended for postgraduate students and researchers whose work involves differential geometry, global analysis, analysis on manifolds, algebraic topology, sheaf theory, cohomology, functional analysis or abstract harmonic analysis.