This volume reprints in a scholar’s edition the first English-language texts on bioethics, John Gregory’s (1724-1773) Observations on the Duties and Offices of a Physician and on the Method of Prosecuting Enquiries in Philosophy (London, 1770) and Lectures on the Duties and Qualifications of a Physician (London, 1772). Five previously unpublished manuscripts of Gregory’s lectures are also included. An introduction places Gregory’s medical ethics and philosophy of medicine in their 18th-century contexts of Scottish Enlightenment history and culture, Baconian science and philosophy of medicine, medical practice, the feminine and feminist philosophy of the Bluestocking Circle, and moral sense philosophy, particularly David Hume’s concept of sympathy, and provides a bibliography of primary and secondary sources as an aid to teaching and future scholarship. The book’s index provides access to Gregory’s texts, by using both historical terms and current terminology of bioethics.