Opening with the Pilgrims in Holland and their journey to Plymouth on the Mayflower, the author dives into the early days of life in Plymouth, highlighting significant events. Chapters in Part I cover the subjects of settlement and land grants, the government and the general court, laws of the colony, the Declaration of Independence, the organization of towns, Burial Hill, the streets, ancient local names, the fire department, schools, and churches. These chapters are followed by a collection of abstracted titles of estates.

The latter half of this work begins after page 350, containing a Genealogical Register which provides records of hundreds of former Plymouth locals and their descendants, making it a great source of historical and genealogical information for anyone interested in the old colony of Plymouth. A full-name, place, and subject index adds to the value of this work.