Science fiction films of the 1930s and 1940s were often set in dark laboratories that had strange looking glass containers, with bubbling fluids and mad scientists conducting glandular and hormonal experiments. In the 1950s, films were more focused on radiation induced mutations. The 1960s and 1970s brought more sophisticated biological sciences to the movies and focused on such relatively new concepts as immunology, cyrobiology, and biochemistry. In the 1980s and 1990s, the focus of science fiction films has been DNA. This work of film criticism relates 71 science fiction films to the biological sciences. The author covers cell biology, pharmacology, endocrinology, hematology, and entomology, to name just a few topics. An analysis of each film includes: a brief plot synopsis, the author’s favourite quotations, the biological principles involved, the accuracy of the laboratory, and correct and incorrect biological information. In his analyses, the author sets out what would be required to achieve in real life the results seen in the movies and whether these experiments or events could actually happen.